| Avera de Smet Memorial Hospital - CAH | De Smet, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Avera Dells Area Hospital - CAH | Dell Rapids, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Avera Flandreau Hospital - CAH | Flandreau, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Avera Gregory Hospital | Gregory, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Avera Hand County Memorial Hospital and Clinic | Miller, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Avera Heart Hospital of South Dakota | Sioux Falls, SD | Acute Care Hospitals | Proprietary | 5 stars |
| Avera McKennan Hospital & University Health Center | Sioux Falls, SD | Acute Care Hospitals | Voluntary non-profit - Private | 4 stars |
| Avera Missouri River Health Center | Gettysburg, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Avera Queen of Peace | Mitchell, SD | Critical Access Hospitals | Voluntary non-profit - Private | 4 stars |
| Avera Sacred Heart Hospital | Yankton, SD | Acute Care Hospitals | Voluntary non-profit - Private | 3 stars |
| Avera St Benedict Health Center - CAH | Parkston, SD | Critical Access Hospitals | Voluntary non-profit - Private | 5 stars |
| Avera St Lukes | Aberdeen, SD | Acute Care Hospitals | Voluntary non-profit - Church | 4 stars |
| Avera St Mary's Hospital | Pierre, SD | Acute Care Hospitals | Voluntary non-profit - Private | 2 stars |
| Avera Weskota Memorial Medical Center - CAH | Wessington Springs, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Bennett County Hospital and Nursing Home - CAH | Martin, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Black Hills Surgical Hospital LLC | Rapid City, SD | Acute Care Hospitals | Proprietary | Not rated |
| Bowdle Hospital - CAH | Bowdle, SD | Critical Access Hospitals | Government - Local | Not rated |
| Brookings Health System | Brookings, SD | Acute Care Hospitals | Government - Local | 4 stars |
| Community Memorial Hospital | Burke, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Community Memorial Hospital | Redfield, SD | Critical Access Hospitals | Government - Local | 4 stars |
| Coteau Des Prairies Health Care System | Sisseton, SD | Critical Access Hospitals | Voluntary non-profit - Private | 4 stars |
| Douglas County Memorial Hospital-CAH | Armour, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Dunes Surgical Hospital | Dakota Dunes, SD | Acute Care Hospitals | Proprietary | Not rated |
| Eagle Butte Indian Health Service Hospital | Eagle Butte, SD | Critical Access Hospitals | Government - Federal | Not rated |
| Eureka Community Health Services - CAH | Eureka, SD | Critical Access Hospitals | Voluntary non-profit - Other | Not rated |
| Fall River Hospital - CAH | Hot Springs, SD | Critical Access Hospitals | Government - Local | Not rated |
| Faulkton Area Medical Center | Faulkton, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Freeman Medical Center - CAH | Freeman, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Hans P Peterson Memorial Hospital - CAH | Philip, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Huron Regional Medical Center | Huron, SD | Critical Access Hospitals | Voluntary non-profit - Private | 2 stars |
| Landmann Jungman Memorial Hospital Corporation | Scotland, SD | Rural Emergency Hospital | Voluntary non-profit - Private | Not rated |
| Lifescape | Sioux Falls, SD | Childrens | Voluntary non-profit - Private | Not rated |
| Madison Regional Health System | Madison, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Marshall County Healthcare Center - CAH | Britton, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Milbank Area Hospital/Avera Health | Milbank, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Mobridge Regional Hospital - CAH | Mobridge, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Monument Health Custer Hospital | Custer, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Monument Health Lead-Deadwood Hospital | Deadwood, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Monument Health Rapid City Hospital | Rapid City, SD | Acute Care Hospitals | Voluntary non-profit - Private | 3 stars |
| Monument Health Spearfish Hospital | Spearfish, SD | Acute Care Hospitals | Voluntary non-profit - Private | 4 stars |
| Monument Health Sturgis Hospital | Sturgis, SD | Critical Access Hospitals | Voluntary non-profit - Other | Not rated |
| PHS Indian Hospital at Rosebud | Rosebud, SD | Acute Care Hospitals | Government - Federal | Not rated |
| Pine Ridge IHS Hospital | Pine Ridge, SD | Acute Care Hospitals | Government - Federal | Not rated |
| Pioneer Memorial Hospital - CAH | Viborg, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Platte Health Center | Platte, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Prairie Lakes Healthcare System, Inc | Watertown, SD | Acute Care Hospitals | Voluntary non-profit - Private | 3 stars |
| Same Day Surgery Center LLC | Rapid City, SD | Acute Care Hospitals | Proprietary | Not rated |
| Sanford Canton-Inwood Medical Center - CAH | Canton, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Sanford Chamberlain Medical Center | Chamberlain, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |
| Sanford Clear Lake Medical Center | Clear Lake, SD | Critical Access Hospitals | Voluntary non-profit - Private | Not rated |