| Shasta Regional Medical Center | Redding, CA | Acute Care Hospitals | 2 stars |
| Sierra Medical Center | El Paso, TX | Acute Care Hospitals | 2 stars |
| Siloam Springs Regional Hospital | Siloam Springs, AR | Acute Care Hospitals | 3 stars |
| Silver Oaks Behavioral Hospital | New Lenox, IL | Psychiatric | Not rated |
| Sinai-Grace Hospital | Detroit, MI | Acute Care Hospitals | 1 star |
| Singing River Gulfport | Gulfport, MS | Acute Care Hospitals | 2 stars |
| Sioux Falls Specialty Hospital | Sioux Falls, SD | Acute Care Hospitals | Not rated |
| Sistersville General Hospital | Sistersville, WV | Critical Access Hospitals | Not rated |
| Smokey Point Behavioral Hospital | Marysville, WA | Psychiatric | Not rated |
| Sonora Behavioral Health Hospital | Tucson, AZ | Psychiatric | Not rated |
| South Arkansas Regional Hospital LLC | El Dorado, AR | Acute Care Hospitals | 3 stars |
| South Georgia Specialty Hospital | Albany, GA | Acute Care Hospitals | Not rated |
| South Sound Behavioral Hospital | Lacey, WA | Psychiatric | Not rated |
| South Texas Health System | Edinburg, TX | Acute Care Hospitals | 4 stars |
| Southcoast Behavioral Health | Dartmouth, MA | Psychiatric | Not rated |
| Southeast Behavioral Hospital | Cape Girardeau, MO | Psychiatric | Not rated |
| Southeastern Regional Medical Center, Inc | Newnan, GA | Acute Care Hospitals | 5 stars |
| Southern California Hospital at Hollywood | Hollywood, CA | Acute Care Hospitals | 3 stars |
| Southern Hills Hospital and Medical Center | Las Vegas, NV | Acute Care Hospitals | 4 stars |
| Southern Tennessee Regional Health System Pulaski | Pulaski, TN | Acute Care Hospitals | 3 stars |
| Southern Tennessee Regional Health System Winchest | Winchester, TN | Acute Care Hospitals | 3 stars |
| Southern Winds Hospital | Hialeah, FL | Psychiatric | Not rated |
| Southwell Medical, A Campus of Trmc | Adel, GA | Acute Care Hospitals | Not rated |
| Southwest Healthcare Rancho Springs Hospital | Murrieta, CA | Acute Care Hospitals | 3 stars |
| Southwest Regional Medical Center LLC | Hope, AR | Acute Care Hospitals | Not rated |
| Southwest Regional Medical Center LLC | Hope, AR | Critical Access Hospitals | Not rated |
| Southwestern Medical Center | Lawton, OK | Acute Care Hospitals | 2 stars |
| Sovah Health Danville | Danville, VA | Acute Care Hospitals | 2 stars |
| Specialists Hospital Shreveport | Shreveport, LA | Acute Care Hospitals | Not rated |
| Spotsylvania Regional Medical Center | Fredericksburg, VA | Acute Care Hospitals | 3 stars |
| Spring Mountain Sahara | Las Vegas, NV | Psychiatric | Not rated |
| Spring Mountain Treatment Center | Las Vegas, NV | Psychiatric | Not rated |
| Spring Valley Hospital Medical Center | Las Vegas, NV | Acute Care Hospitals | 3 stars |
| Spring View Hospital | Lebanon, KY | Acute Care Hospitals | 5 stars |
| Springbrook Behavioral Health System | Travelers Rest, SC | Psychiatric | Not rated |
| Springhill Medical Center | Mobile, AL | Acute Care Hospitals | 3 stars |
| Springwoods Behavioral Health Services | Fayetteville, AR | Psychiatric | Not rated |
| SSM Health St. Mary's Hospital - Jefferson City | Jefferson City, MO | Acute Care Hospitals | 3 stars |
| St Christopher's Hospital for Children | Philadelphia, PA | Childrens | Not rated |
| St David's Medical Center | Austin, TX | Acute Care Hospitals | 4 stars |
| St David's South Austin Medical Center | Austin, TX | Acute Care Hospitals | 3 stars |
| St Elizabeth Medical Center | Wabasha, MN | Critical Access Hospitals | Not rated |
| St Francis Hospital | Memphis, TN | Acute Care Hospitals | 1 star |
| St Joseph Health System, LLC | Fort Wayne, IN | Acute Care Hospitals | 4 stars |
| St Joseph Medical Center | Kansas City, MO | Acute Care Hospitals | 3 stars |
| St Joseph's Behavioral Health Center | Stockton, CA | Psychiatric | Not rated |
| St Lucie Medical Center | Port Saint Lucie, FL | Acute Care Hospitals | 1 star |
| St Luke's Hospital - Upper Bucks Campus | Quakertown, PA | Acute Care Hospitals | 5 stars |
| St Luke's McCall | McCall, ID | Critical Access Hospitals | Not rated |
| St Luke's Patients Medical Center | Pasadena, TX | Acute Care Hospitals | 3 stars |