| Seiling Municipal Hospital | Seiling, OK | Critical Access Hospitals | Not rated |
| Seneca District Hospital | Chester, CA | Critical Access Hospitals | Not rated |
| Sentara Albemarle Medical Center | Elizabeth City, NC | Acute Care Hospitals | 3 stars |
| Seymour Hospital | Seymour, TX | Critical Access Hospitals | Not rated |
| SGMC Health | Valdosta, GA | Acute Care Hospitals | 2 stars |
| SGMC Health Lanier | Lakeland, GA | Critical Access Hospitals | Not rated |
| Share Medical Center | Alva, OK | Critical Access Hospitals | Not rated |
| Shoshone Medical Center | Kellogg, ID | Critical Access Hospitals | 3 stars |
| Skagit Valley Hospital | Mount Vernon, WA | Acute Care Hospitals | 3 stars |
| Skyline Hospital | White Salmon, WA | Critical Access Hospitals | Not rated |
| Slidell Memorial Hospital | Slidell, LA | Acute Care Hospitals | 2 stars |
| Snoqualmie Valley Hospital | Snoqualmie, WA | Critical Access Hospitals | Not rated |
| So Crescent Beh Hlth Sys - Anchor Hospital Campus | College Park, GA | Psychiatric | Not rated |
| Sonoma Valley Hospital | Sonoma, CA | Acute Care Hospitals | 2 stars |
| South Big Horn County Hospital | Basin, WY | Critical Access Hospitals | Not rated |
| South Lincoln Medical Center - CAH | Kemmerer, WY | Critical Access Hospitals | Not rated |
| Southeast Colorado Hospital District | Springfield, CO | Critical Access Hospitals | Not rated |
| Southeast Georgia Health System -- Camden Campus | Saint Marys, GA | Acute Care Hospitals | 4 stars |
| Southeast Georgia Health System- Brunswick Campus | Brunswick, GA | Acute Care Hospitals | 2 stars |
| Southeast Health Medical Center | Dothan, AL | Acute Care Hospitals | 4 stars |
| Southern Coos Hospital & Health Center | Bandon, OR | Critical Access Hospitals | 2 stars |
| Southern Inyo Hospital | Lone Pine, CA | Critical Access Hospitals | Not rated |
| Spanish Peaks Regional Health Center | Walsenburg, CO | Critical Access Hospitals | Not rated |
| Sparta Community Hospital | Sparta, IL | Critical Access Hospitals | 3 stars |
| Spartanburg Medical Center | Spartanburg, SC | Acute Care Hospitals | 2 stars |
| St Bernard Parish Hospital | Chalmette, LA | Acute Care Hospitals | 4 stars |
| St Charles Parish Hospital | Luling, LA | Acute Care Hospitals | Not rated |
| St Helena Parish Hospital | Greensburg, LA | Critical Access Hospitals | Not rated |
| St James Parish Hospital | Lutcher, LA | Critical Access Hospitals | Not rated |
| St Johns Medical Center | Jackson, WY | Acute Care Hospitals | 5 stars |
| St Luke Hospital & Living Center | Marion, KS | Critical Access Hospitals | Not rated |
| St Tammany Parish Hospital | Covington, LA | Acute Care Hospitals | 4 stars |
| St Vincent General Hospital District | Leadville, CO | Critical Access Hospitals | Not rated |
| Star Valley Medical Center | Afton, WY | Critical Access Hospitals | Not rated |
| Starr County Memorial Hospital | Rio Grande City, TX | Acute Care Hospitals | 2 stars |
| Ste Genevieve County Memorial Hospital | Sainte Genevieve, MO | Critical Access Hospitals | 4 stars |
| Stephens County Hospital | Toccoa, GA | Acute Care Hospitals | 2 stars |
| Stephens Memorial Hospital | Breckenridge, TX | Critical Access Hospitals | Not rated |
| Stillwater Medical - Perry | Perry, OK | Rural Emergency Hospital | Not rated |
| Stillwater Medical Center | Stillwater, OK | Acute Care Hospitals | 4 stars |
| Stillwater Medical-Blackwell | Blackwell, OK | Rural Emergency Hospital | Not rated |
| Stonewall Memorial Hospital District | Aspermont, TX | Critical Access Hospitals | Not rated |
| Sublette County Health | Pinedale, WY | Acute Care Hospitals | Not rated |
| Summit Pacific Medical Center | Elma, WA | Critical Access Hospitals | 2 stars |
| Surprise Valley Community Hospital | Cedarville, CA | Critical Access Hospitals | Not rated |
| Sutter Coast Hospital | Crescent City, CA | Acute Care Hospitals | 2 stars |
| Sweeny Community Hospital | Sweeny, TX | Critical Access Hospitals | Not rated |
| Syracuse Area Health | Syracuse, NE | Critical Access Hospitals | Not rated |
| Tahoe Forest Hospital | Truckee, CA | Critical Access Hospitals | 3 stars |
| Tanner Medical Center - Carrollton | Carrollton, GA | Acute Care Hospitals | 2 stars |